Pre_GI Gene

Host: NC_004631:1182883 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:1182883 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
118203511828868524-diphosphocytidyl-2-C-methyl-D-erythritol kinaseQuickGO ontologyBLASTP
11828831183506624outer membrane lipoprotein LolB precursorQuickGO ontologyBLASTP
118382011850761257glutamyl-tRNA reductaseQuickGO ontologyBLASTP
118511711861991083peptide chain release factor 1QuickGO ontologyBLASTP
11861991187032834N5-glutamine S-adenosyl-L-methionine-dependent methyltransferaseQuickGO ontologyBLASTP
11870291187418390putative regulatorQuickGO ontologyBLASTP
11874221188231810putative regulatorQuickGO ontologyBLASTP
118826911891238552-dehydro-3-deoxyphosphooctonate aldolaseQuickGO ontologyBLASTP
11893171189775459transposase for insertion sequence element IS200QuickGO ontologyBLASTP
119028011914041125putative bacteriophage proteinQuickGO ontologyBLASTP
11924451192858414putative pertussis-like toxin subunitQuickGO ontologyBLASTP
11928751193603729putative pertussis-like toxin subunitQuickGO ontologyBLASTP
11937951194337543hypothetical proteinBLASTP
11944851194862378hypothetical proteinBLASTP
11949351195744810putative toxin-like proteinQuickGO ontologyBLASTP
11961991196405207BLASTP
11966171196856240putative virulence proteinQuickGO ontologyBLASTP
11970471197568522putative lipoproteinQuickGO ontologyBLASTP
11979861198198213putative cold shock proteinQuickGO ontologyBLASTP
11983301198593264putative outer membrane virulence proteinQuickGO ontologyBLASTP
11986421198806165hypothetical proteinBLASTP
11988921199020129hypothetical proteinBLASTP
11993981199955558outer membrane invasion proteinQuickGO ontologyBLASTP
11999661200136171hypothetical proteinBLASTP
12006881200861174hypothetical proteinBLASTP
12011891201530342putative secreted proteinQuickGO ontologyBLASTP
1201602120169190hypothetical proteinBLASTP
1201746120183590hypothetical proteinBLASTP
12019111202036126putative lipoproteinQuickGO ontologyBLASTP
12022361202463228hypothetical proteinBLASTP
12026581203128471putative heat shock proteinQuickGO ontologyBLASTP
12032371203386150hypothetical proteinBLASTP
120346712045101044hypothetical proteinBLASTP
12045931205123531putative cytochromeQuickGO ontologyBLASTP
12052721205586315putative lipoproteinQuickGO ontologyBLASTP
120629012079241635putative substrate-binding transport proteinQuickGO ontologyBLASTP
12079211208898978putative inner membrane transport proteinQuickGO ontologyBLASTP
12088881209700813putative inner membrane transport proteinQuickGO ontologyBLASTP
12096941210491798putative ABC transport ATP-binding proteinQuickGO ontologyBLASTP
12104851211075591putative ABC transport ATP-binding subunitQuickGO ontologyBLASTP
121115712122901134hypothetical proteinBLASTP
12124841212810327hypothetical proteinBLASTP
12130041213654651hypothetical proteinBLASTP
12137631214551789aminoglycoside-resistance proteinQuickGO ontologyBLASTP