Pre_GI Gene

Host: NC_005957:667954 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005957:667954 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
667041667967927oligopeptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
6679546689731020oligopeptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
6692586706071350glycerol-3-phosphate transporterQuickGO ontologyBLASTP
670880671338459transcriptional regulator MarR familyQuickGO ontologyBLASTP
6713586729711614multidrug resistance protein B sugar and other transporterQuickGO ontologyBLASTP
673109674080972ribose operon repressorQuickGO ontologyBLASTP
674094674990897ribokinaseQuickGO ontologyBLASTP
674987675382396ribose ABC transporter permeaseQuickGO ontologyBLASTP
6754016768851485ribose ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
676888677823936ribose ABC transporter permeaseQuickGO ontologyBLASTP
677838678764927ribose ABC transporter ribose-binding proteinQuickGO ontologyBLASTP
678799679446648transaldolaseQuickGO ontologyBLASTP
6797646821632400immune inhibitor A metalloproteaseQuickGO ontologyBLASTP
682482682823342hypothetical proteinBLASTP
6828606840321173probable multidrug efflux transporterQuickGO ontologyBLASTP
6842586853101053zinc-containing alcohol dehydrogenase long-chainQuickGO ontologyBLASTP
685429685773345conserved hypothetical protein possible potassium channel proteinQuickGO ontologyBLASTP
686027686878852phospholipase CQuickGO ontologyBLASTP
6868176879531137sphingomyelin phosphodiesteraseQuickGO ontologyBLASTP
6880616892331173hypothetical proteinBLASTP
6892216905341314probable FAD-dependent oxidoreductaseQuickGO ontologyBLASTP