Pre_GI Gene

Host: NC_011725:2365647 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011725:2365647 Bacillus cereus B4264 chromosome, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was isolated in 1969 from a case of fatal pneumonia in a male patient. B. cereus B4264 was cultured from the blood and the pleural fluid. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
236564723721176471linear gramicidin synthetase subunit DQuickGO ontologyBLASTP
2372114238699614883bacitracin synthetase 1QuickGO ontologyBLASTP
238743823880646274-phosphopantetheinyl transferaseQuickGO ontologyBLASTP
23880512388773723thioesteraseQuickGO ontologyBLASTP