Pre_GI Gene

Host: NC_008600:5113765 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008600:5113765 Bacillus thuringiensis str. Al Hakam, complete genome

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
51130345113768735ABC transporter permease componentQuickGO ontologyBLASTP
51137655114667903ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
51148255115619795methionine aminopeptidaseQuickGO ontologyBLASTP
511642951263919963collagen adhesion proteinQuickGO ontologyBLASTP
512684051282791440aminopeptidaseQuickGO ontologyBLASTP
51284285128802375hypothetical proteinBLASTP
51288285129499672possible ECF-type sigma factor negative effectorQuickGO ontologyBLASTP
51297845130407624RNA polymerase sigma-70 factor ECF subfamilyQuickGO ontologyBLASTP
513045751321271671arginine--tRNA ligaseQuickGO ontologyBLASTP
51321275132582456hypothetical proteinBLASTP